Current Issue : April - June Volume : 2016 Issue Number : 2 Articles : 2 Articles
Maleimide is considered as a biologically important active scaffold that possesses almost all types of biological activities includes antibacterial and antifungal activity, anticancer activity, cox-2 inhibitor and anti-inflammatory, antidiabetic activity, monoglyceride lipase inhibitor activity, antistress activity, glycogen synthase-3 (GSK-3) inhibitor activity, photodynamic activity and angiogenesis inhibitor activity. This review is complementary to earlier research work of on various biological activities of maleimide derivatives....
The objective this research work was to synthesize a new series of 3-((5-((6-(phenylthio)-1H-Benz[d]imidazol-2-yl) amino)-1, 3, 4-oxadiazol-2-yl) imino) substituted indolin-2-ones and evaluated for cytotoxic, anti oxidant and anti-inflammatory activity. All the compounds were screened by MTT assay, DPPH, TMPD assay method. The results of this study revealed that all synthesized compounds significantly shown concentration dependent manner. All the synthesized compounds have shown moderate cytotoxic, antioxidant and less anti-inflammatory activity....
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